A systematic review of mathematical models of mosquito-borne pathogen transmission: 1970–2010

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A systematic review of mathematical models of mosquito-borne pathogen transmission: 1970–2010

Mathematical models of mosquito-borne pathogen transmission originated in the early twentieth century to provide insights into how to most effectively combat malaria. The foundations of the Ross-Macdonald theory were established by 1970. Since then, there has been a growing interest in reducing the public health burden of mosquito-borne pathogens and an expanding use of models to guide their co...

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The Ross-Macdonald model has dominated theory for mosquito-borne pathogen transmission dynamics and control for over a century. The model, like many other basic population models, makes the mathematically convenient assumption that populations are well mixed; i.e., that each mosquito is equally likely to bite any vertebrate host. This assumption raises questions about the validity and utility o...

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Mosquito-borne diseases pose some of the greatest challenges in public health, especially in tropical and sub-tropical regions of the world. Efforts to control these diseases have been underpinned by a theoretical framework developed for malaria by Ross and Macdonald, including models, metrics for measuring transmission, and theory of control that identifies key vulnerabilities in the transmiss...

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ژورنال

عنوان ژورنال: Journal of The Royal Society Interface

سال: 2013

ISSN: 1742-5689,1742-5662

DOI: 10.1098/rsif.2012.0921